Evaluation of pyruvate kinase and oxidative stress parameters in differentiation between transudate and exudate in pleural liquids

نویسندگان

چکیده

Abstract Objectives We aimed to investigate the usability of pleural pyruvate kinase (PK), total antioxidant status (TAS), and oxidant (TOS) as an alternative Light’s criteria in exudate-transudate differentiation. Methods This prospective study was conducted among 84 patients (42 transudates 42 exudates) with effusion. The levels PK, TAS, TOS were measured by using ELISA kits, ROC analysis used evaluate diagnostic efficiency . Results PK (p=0.001), TAS (p=0.027), (p=0.002) fluids found be significantly higher exudate group. cut-off values for 10.64 U/L, 13.54 mmol trolox equivalent/L, 13.88 μmol H 2 O respectively. While sensitivity 97.62 % 66.67 64.29 TOS, specificity 80.95 52.38 57.14 TOS. Conclusions effusion can useful suspected cases differentiate between transudate addition criteria. However, parameters could not sensitive specific

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ژورنال

عنوان ژورنال: Türk biyokimya dergisi

سال: 2023

ISSN: ['1303-829X']

DOI: https://doi.org/10.1515/tjb-2022-0255